Is the HSIL Subclassification Cytologically Real and Clinically JustifiedReport as inadecuate

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Collegium antropologicum, Vol.34 No.2 June 2010. -

The aim of the study was to evaluate the justification of Croatian modification of Bethesda classification after thirteen years of its application, answering the question if the subclassification of high-grade squamous intraepithelial lesion HSIL into cervical intraepithelial lesion CIN grade 2 CIN2 and grade 3 CIN3 is cytologically real and clinically justified. The retrospective study included 3110 women to whom cervical intraepithelial lesion of different grade was diagnosed by cytological examination of vaginal-cervical-endocervical VCE smear at Department of Clinical Cytology, Clinical hospital Osijek in period from 1993 to 2005. 57.1% of women were monitored cytologically and colposcopically, while 42.9% of them had also pathohistological examination. The spontaneous regression of cytological finding was noted in 66.3% of the cases. Moderate dysplasia regressed more often 50.98% than severe dysplasia 31.3% and more rarely than mild dysplasia 70.1%, which was statistically significant p

Author: Valerija Miličić-Juhas - Marija Pajtler -



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