Effect of Botulinum Toxin-A Injection on Intraocular Pressure and Proptosis in Thyroid Associated OrbitopathyReportar como inadecuado




Effect of Botulinum Toxin-A Injection on Intraocular Pressure and Proptosis in Thyroid Associated Orbitopathy - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Collegium antropologicum, Vol.33 No.4 December 2009. -

The aim of this study was to evaluate the effects of extraocular muscle injection of botulinum toxin-A BTX-A on intraocular pressure IOP and proptosis in patients with ocular motility disturbances in thyroid associated orbitopathy TAO. In 17 patients 20 eyes with restrictive strabismus and diplopia, BTX -A injections were applied. Intraocular pressure was measured with a Goldmann applanation tonometer in primary gaze position before and 2–4 weeks after BTX-A injection. Extraorbital prominention of the eyeball was measured before and after BTX -A injection using a Hertel instrument. Before the injection, the mean IOP in primary position of gaze was 18.6± 2.8 mmHg and 2–4 weeks after BTX-A injection was 16.9±3.3 mmH; p=0.001. There was no statistically significant difference in Hertel egzophthalmometer readings before and after BTX-A injection, 21.5±2.7 mm vs 22.0± 2.6 mm; p=0.678. In conclusion, BTX-A injection has a secondary lowering effect on IOP in TAO due to relaxation of extraocular muscles, but with no influence on proptosis.

thyroid related orbitopathy; botulinum toxin-A; intraocular pressure; proptosis



Autor: Mladen Lešin - ; Eye Department, University Hospital Center Split, Split, Croatia Lovro Bojić - ; Eye Department, University Ho

Fuente: http://hrcak.srce.hr/



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