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From personality to neuropsychiatric disorders, individual differences in brain function are known to have a strong heritable component. Here we report that between close relatives, a variety of neuropsychiatric disorders covary strongly with intellectual interests. We surveyed an entire class of high-functioning young adults at an elite university for prospective major, familial incidence of neuropsychiatric disorders, and demographic and attitudinal questions. Students aspiring to technical majors science-mathematics-engineering were more likely than other students to report a sibling with an autism spectrum disorder p = 0.037. Conversely, students interested in the humanities were more likely to report a family member with major depressive disorder p = 8.8×10−4, bipolar disorder p = 0.027, or substance abuse problems p = 1.9×10−6. A combined PREdisposition for Subject MattEr PRESUME score based on these disorders was strongly predictive of subject matter interests p = 9.6×10−8. Our results suggest that shared genetic and perhaps environmental factors may both predispose for heritable neuropsychiatric disorders and influence the development of intellectual interests.



Autor: Benjamin C. Campbell, Samuel S.-H. Wang

Fuente: http://plos.srce.hr/



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