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Aim: Few stress markers are available for women in perinatal period. We introduced biopyrrin BPn for monitoring the perinatal stress and investigated how the stress could be regulated. Methods: Study patients consisted of 220 full-term pregnant women between 2006 and 2008. Cases were analyzed based on 1 pattern of delivery, the use of pain control anesthesia or hypnotics Sophrology, 2 maternal complications, and 3 habitual smoking or alcohol consumption. Urinary samples were collected from pregnant women before and after delivery, and from newborn babies. Results: The average level of BPn in pregnant women was 2.61 ± 0.25 U-g·Creatinin Cre. Mean ± SE. This is significantly higher than age-matched non-pregnant women 0.79 ± 0.24 U-g·Cre. After normal delivery, BPn was significantly elevated to 5.29 ± 0.57 U-g·Cre p < 0.001. BPn decreased significantly to 3.41 ± 0.51 U-g·Cre in sophrology assisted delivery and 4.87 ± 0.53 U-g·Cre under epidural anesthesia p < 0.05, while delivery induction elevated BPn 11.62 ± 1.95 U-g·Cre. Conclusions: BPn might be an excellent indicator for monitoring perinatal stress. Significant decrease of BPn in sophrology-assisted delivery suggests that the technique should be useful for the relief of perinatal stress.


Biopyrrin; Oxidative Stress; Sophrology; Anesthesia

Cite this paper

Suzuki, M. , Isonishi, S. , Morimoto, O. , Ogawa, M. and Ochiai, K. 2012 Effect of sophrology on perinatal stress monitored by biopyrrin. Open Journal of Obstetrics and Gynecology, 2, 176-181. doi: 10.4236-ojog.2012.22036.

Autor: Michiko Suzuki, Seiji Isonishi, Osamu Morimoto, Masahisa Ogawa, Kazuhiko Ochiai

Fuente: http://www.scirp.org/


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