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Neutrophilic leukocytosis above 50 × 109-l exclude leukemia, defines a leukemoid reaction LR. It is associated with several diseases. Although it simulates leukemia, most of the causes are benign. Tumor-related LR is more common. It is associated with ranulocyte colony-stimulating factor G-CSF secreted by the tumor cells. A 38-year-old woman, presented with advanced breast cancer and leukocytosis 79.9 × 103-uL was found. After completion of MRM, the condition of leukocytosis subsided. Two months later, tumor local relapse was found and white blood cells WBC rose again. After completion of wide excision, the condition of leukocytosis subsided again. We think this case was associated with leukemoid reaction.


Leukemoid Reaction; Leukocytosis; Breast Cancer

Cite this paper

C. Lin, J. Yu, J. Ou, Y. Lee and H. Wu -Leukemoid Reaction as a -Tumor Marker- in Breast Cancer,- Surgical Science, Vol. 3 No. 5, 2012, pp. 271-273. doi: 10.4236-ss.2012.35054.

Autor: Chien-Hua Lin, Jyh-Cherng Yu, Jing-Jim Ou, Yueh-Tsung Lee, Hurng-Sheng Wu

Fuente: http://www.scirp.org/


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