Antibacterial and Antioxidant Properties of N-Carboxyethyl ChitosanReport as inadecuate

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chitosan is the only alkaline natural polysaccharide, which expresses good bioactivities. In this paper, chitosan was modified with pyruvic acid to get N-carboxyethyl chitosan N-CE-CTS which was supposed to have better solubility and bioactivities than chitosan. N-CE-CTS with DS 40.1% dissolves in water. Antioxidant activity was measured with electron spinning resonance ESR. The results show that N-CE-CTS has better antioxidant activity than chitosan. The antioxidant activity of 2 mg-mL N-CE-CTS and chitosan is 35.0% and 30.1%, respectively. N-CE-CTS has good antibacterial activity against Staphylococcus aureus and Escherichia coli. However antibacterial activity of N-CE-CTS is a little lower than that of chitosan. Antioxidant and antibacterial activity of N-CE-CTS and chitosan increase with the increase of concentration of N-CE-CTS and chitosan.


chitosan, N-carboxyethyl chitosan, antioxidant activity, antibacterial activity

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Author: Chang-jiang Yu, Qiang Lin, Wen Yuan, Fang Liu



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