Preparation and Protein Adsorption of Type I Collagen of Anti-Biofouling Film Based on Liquid Crystal-Polymer CompositeReport as inadecuate




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Hydroxypropyl cellulose propionate PPC could be synthesized by esterification with hydroxypropyl cellulose HPC and propionyl chloride. The chemical structure and morphology of the PPC were characterized by IR, NMR and polarizing optical microscopy POM, respectively. It was found that PPC degree of substitution = 2.06 displays in the form of cholesteric liquid crystal around the body temperature of 37℃.PPC-polyvinyl chloride PVC blend films with different liquid crystal content were prepared by solvent evaporation, and their protein adsorption at 37℃ temperature was measured by hydroxyproline method using collagen I. The results showed that the addition of PPC could significantly reduce the protein adsorption amount of collagen I on the PPC-PVC blend films, and the protein adsorption of blend films was affected by not only the content of PPC but also the morphology of liquid crystal domain. PPC may provide an alternative strategy for the development of anti-biofouling polymeric materials.

KEYWORDS

cellulose; blend films; I collagen; anti-biofouling

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Author: Lei Gong, Rong Zeng, Jing-yun Ye, Mei Tu, Jian-hao Zhao, Chang-ren Zhou

Source: http://www.scirp.org/



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