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Collegium antropologicum, Vol.30 No.4 December 2006. -

Hemophagocytic syndrome HPS is a rare condition characterized by overactive histiocytes, hepatosplenomegaly, fever

and cytopenia, with two major types: familial, autosomal recessive genetic disease and acquired that can occur during

systemic infections, immunodeficiency or malignancy. Inappropriate activation of macrophages by cytokines is the

major mechanism of the disease. We report a case of an adult patient with HPS. After thorough clinical investigation, we

have not been able to establish the underlying disease, and corticosteroids therapy was initiated empirically. After 8

months follow-up the patient is well with normal laboratory findings.

hemophagocytic syndrome; hemophagocytic lymphohistiocitosis; secondary



Autor: Ivan Gornik - Vladimir Gašparović -

Fuente: http://hrcak.srce.hr/



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