Determinants of Use of Intermittent Preventive Treatment of Malaria in Pregnancy: Jinja, UgandaReportar como inadecuado

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Maternal malaria is associated with serious adverse pregnancy outcomes. One recommended means of preventing malaria during pregnancy is intermittent preventive therapy IPTp with sulfadoxine-pyrimethamine SP. We sought to identify determinants of preventive use of SP during pregnancy among recently pregnant women in Uganda. Additionally, we characterized the timing of and indications for the administration of SP at antenatal care ANC visits and missed opportunities for SP administration.

Methodology-Principal Findings

Utilizing a population-based random sample, we interviewed 500 women living in Jinja, Uganda who had been pregnant in the past year. Thirty-eight percent 192-500 of women received SP for the treatment of malaria and were excluded from the analysis of IPTp-SP. Of the remaining women, 275 89.3% reported at least two ANC visits after the first trimester and had an opportunity to receive IPTp-SP according to the Ugandan guidelines, but only 86 31.3% of these women received a full two-dose course of IPTp. The remaining 189 68.7% women missed one or more doses of IPTp-SP. Among the 168 women that were offered IPTp, 164 97.6% of them took the dose of SP.


Use of IPTp in Uganda was found to be far below target levels. Our results suggest that women will take SP for IPTp if it is offered during an ANC visit. Missed opportunities to administer IPTp-SP during ANC were common in our study, suggesting provider-level improvements are needed.

Autor: Laura R. Sangaré , Andy Stergachis, Paula E. Brentlinger, Barbra A. Richardson, Sarah G. Staedke, Mpungu S. Kiwuwa, Noel S. Weis



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