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Collegium antropologicum, Vol.32 No.1 May 2008. -

The aim of this study was to determine level of serum IgA, IgG and IgM in patients with OLR as indicators of

humoral immunity which might reflect cell-mediated immunity. This study was conducted on 30 patients age 60.17±

11.75 with clinically and histopathologically confirmed diagnosis of OLR and 30 healthy controls age 56.16±11.82

Determination of serum IgA, IgG and IgM was performed by use of standard laser nephelometry in both patients and

controls. Statistical analysis was done using Mann-Whitney U test and the level of significance was determined as p values

lower than 0.05. Serum IgA and IgM in patients with OLR were significantly increased in comparison to the control

group, while serum IgG levels were higher in patients with OLR but they did not reach significance. We might conclude

that elevated levels of serum IgA and IgM show that humoral immunity is implicated in the pathogenesis of OLR.

serum immunoglobulin A; G; M; oral lichen ruber



Autor: Dolores Biočina-Lukenda - Ana Cekić-Arambašin - Jasenka Markeljević - Dino Buković -

Fuente: http://hrcak.srce.hr/



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