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Collegium antropologicum, Vol.32 No.1 May 2008. -

To determine the newborn infection rate with group B streptococcus infection GBS before and after American Academy

of Pediatrics Protocol AAP implementation in Croatia, antenatal risk factors, neonatal outcome and necessity for

introducing national policy for intrapartum chemoprophylaxis. To evaluate the role of intrapartum chemoprophylaxis in

preterm labor at 12 hours 49.3%,

chorioamnionitis 11.9%, status post cerclage 10.4%, diabetes mellitus 4.5%, delivery out of hospital 3%, uroinfection

1.5%. After AAP implementation the incidence of GBS infection decreased from 15-1000 to 10-1000 of live born

infants. The mortality from EOGBS dropped from 5% to 3 %. The incidence of GBS infection in our study was considerably

higher than in all current reports. Reasons for that can be inadequate perinatal screen in some parts of the country

and no established policy for intrapartum antibiotic treatment of women with risk factors. Our results documented that

intrapartum chemo-prophylaxis for GBS infection significantly reduces perinatal mortality due to neonatal infection

and sepsis.

Group B streptococcus infection; neonatal outcome; prophylaxis; prevention



Autor: Vesna Elveđi-Gašparović - Branimir Peter -

Fuente: http://hrcak.srce.hr/



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