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Abstract: Codon usage bias measure is defined through the mutual entropy calculation ofreal codon frequency distribution against the quasi-equilibrium one. Thislatter is defined in three manners: 1 the frequency of synonymous codons issupposed to be equal i.e., the arithmetic mean of their frequencies; 2 itcoincides to the frequency distribution of triplets; and, finally, 3 thequasi-equilibrium frequency distribution is defined as the expected frequencyof codons derived from the dinucleotide frequency distribution. The measure ofbias in codon usage is calculated for 125 bacterial genomes.



Author: Michael G.Sadovsky, Julia A.Putintzeva

Source: https://arxiv.org/







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