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Fulminant myocarditis is commonly recognized as an acute myocarditis with cardiogenic shock requiring mechanical support systems. Before the development of mechanical assist devices, previous study described that most of patients with fulminant myocarditis die at acute phase because of rapidly progressive cardiac decompensation. To investigate the feature of myocarditis, we checked consecutive 18 patients 10 men, 8 women, 12yr-80yr from April in 2001 to September 2008 in University. Of these patients 3 needed intraaortic balloon pumping IABP 2 men, 1 woman, 6 did both IABP and percutaneous cardiopulmonary support PCPS 2 men, 4 women. Three patients who need both IABP and PCPS died 2 men, 49yr and 65yr, 1 woman, 54yr because of uncontrolled bacterial infection. No patients whose age was under 40yr 5 men, 4 women died although a man needed IABP and 3 women did both IABP and PCPS. Sixteen patients were able to resume a normal life although 1 male patient needed permanent pacemaker, 1 female did cardiac resynchronization therapy, and a male and a female had left ventricular systolic dysfunction. In conclusion, the young patients had better prognosis than older even if mechanical assist is needed. Although half of patients needed mechanical assist, the prevention of multi-organ complications including bacterial infection is one of the most important keys in the treatment of fulminant myocarditis.

KEYWORDS

Myocarditis, Mechanical Support, Immunosuppressive Therapy, Immunomodulation Therapy

Cite this paper

H. Kawano, Y. Nagayoshi, S. Kojima, N. Kakihara, S. Sakuma, M. Uchino, A. Komatsu, M. Asaka, M. Shimomura, H. Yamabe, H. Ogawa and K. Node -Clinical Feature of Japanese Patients with Fulminant Myocarditis—Myocarditis in Japanese Patients,- International Journal of Clinical Medicine, Vol. 2 No. 3, 2011, pp. 260-263. doi: 10.4236-ijcm.2011.23041.





Autor: Hiroaki Kawano, Yasuhiro Nagayoshi, Sunao Kojima, Nahoko Kakihara, Satoshi Sakuma, Masumi Uchino, Aiko Komatsu, Machiko Asaka, Mi

Fuente: http://www.scirp.org/



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