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Background: research focusing on incidence of cancer amongst bipolar affective disorder BAD is sparse. Aim: to ex-amine the incidence of cancer in a cohort of BAD inpatients. Methods: the study sample was comprised of BAD patients who had been admitted to a tertiary care mental health center during the period: 1990 to 2006. The data for the sample was cross-referenced with the National Cancer Registry. Analyses of Standardized Incidence Rates SIR for all organ systems malignancies were performed. Results: of 1,638 BAD patients included in the present study, 72 0.04% were diagnosed as suffering from co-morbid malignancy. This reflects a significantly reduced risk; SIR of 0.27 95% CI 0.21-0.34. Reduced risk of cancer held true for both males and females 0.20 and 0.34, respectively. Nineteen women developed breast cancer; SIR = 0.42 95% CI 0.25-0.66. Conclusions: the present study demonstrates reduced rates of cancer amongst patients suffering from BAD - with special reduction in breast cancer.


Bipolar Affective Disorder, Cancer, Tertiary Care

Cite this paper

E. Rosenshfir, P. Shemesh, D. Aizenberg and Y. Barak -Reduced Risk of Cancer in Patients with Bipolar Affective Disorder,- Neuroscience and Medicine, Vol. 2 No. 1, 2011, pp. 57-60. doi: 10.4236-nm.2011.21008.

Autor: Eyal Rosenshfir, Pnina Shemesh, Dov Aizenberg, Yoram Barak



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