Healing potential of Anogeissus latifolia for dermal wounds in ratsReportar como inadecuado




Healing potential of Anogeissus latifolia for dermal wounds in rats - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Acta Pharmaceutica, Vol.54 No.4 December 2004. -

Wound healing potential of etnanolic extract of Anogeissus latifolia bark ALE for treatment of dermal wounds in rats was studied on excision and incision wound models. HPTLC of the total extract was recorded for the purpose of standardization. Various parameters of incision wound, viz. epithelization period, scar area, tensile strength and hydroxyproline measurements along with wound contraction, were used to evaluate the effect of A. latifolia on wound healing. The results obtained indicate that A. latifolia accelerates the wound healing process by decreasing the surface area of the wound and increasing the tensile strength. Nitrofurazone ointment was used as a positive control. Complete epithelization was observed within 15 days with ALE. Measurements of the healed area and the hydroxyproline level were in agreement. Antibacterial activity of ALE was studied against Gram-positive Staphylococcus aureus and Gram-negative bacteria Escherichia coli, Pseudomonas aeruginosa and Klebsiella pneumoniae compared to erythromycin and tetracycline. Moderate activity was observed against all organisms. The present study provides a scientific rationale for the traditional use of Anogeissus latifolia in the management of skin diseases such as sores, boils and itching.

Anogeissus latifolia Combretaceae; wound healing; antibacterial activity; HPTLC



Autor: RAGHAVAN GOVINDARAJAN - MADHAVAN VIJAYAKUMAR - CHANDANA VENKATESHWARA RAO - ANNIE SHIRWAIKAR - SHANTA MEHROTRA - PALPU PUSHPANGAD

Fuente: http://hrcak.srce.hr/



DESCARGAR PDF




Documentos relacionados