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In this work, we propose a model of the coronary circulation based on hydraulic-electric analogy. This model aims to provide quantitative estimations of the distribution of flows and pressures across the coro-nary network for patients with stenoses of the left main coronary artery LMCA, left anterior de-scending artery LAD and left circumflex branch LCx, and chronic occlusion of the right coronary artery RCA, undergoing off-pump coronary sur-gery. The results of the simulations are presented for 10 patients with various stenoses grades and collat-eral supply. For each patient, the four revasculariza-tion situations no graft operating, pathological situa-tion 0G; right graft only 1G, left grafts only 2G, complete revascularization 3G are considered. It is shown that: 1 the complete revascularization is fully justified for these patients because neither the right graft alone, nor the left grafts alone can ensure a suf-ficient perfusion improvement for the heart; 2 the capillary and collateral resistances and the propor-tion between them have a major impact on the flows and pressures everywhere in the network; 3 in the presence of the left grafts, the flows in the native stenosed arteries become low and this could promote the development of the native disease in these branches.


Coronary Disease; Off-Pump Surgery; Patients- Specific Simulations; Lumped Parameter Model

Cite this paper

Maasrani, M. , Abouliatim, I. , Harmouche, M. , Verhoye, J. , Corbineau, H. and Drochon, A. 2011 Patients- specific simulations of coronary fluxes in case of three-vessel disease. Journal of Biomedical Science and Engineering, 4, 34-45. doi: 10.4236-jbise.2011.41005.

Autor: Mahmoud Maasrani, Issam Abouliatim, Majid Harmouche, Jean-Philippe Verhoye, Hervé Corbineau, Agnès Drochon



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