Cowpox virus: What’s in a NameReportar como inadecuado


Cowpox virus: What’s in a Name


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1

Poxvirus and Rabies Branch, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA 30333, USA

2

Oak Ridge Institute for Science and Education, P.O. Box 117, Oak Ridge, TN 37831, USA

3

Bundeswehr Institute of Microbiology, Neuherbergstr 11, 80937 Munich, Germany



These authors contributed equally to this work.





*

Author to whom correspondence should be addressed.



Academic Editor: Eric O. Freed

Abstract Traditionally, virus taxonomy relied on phenotypic properties; however, a sequence-based virus taxonomy has become essential since the recent requirement of a species to exhibit monophyly. The species Cowpox virus has failed to meet this requirement, necessitating a reexamination of this species. Here, we report the genomic sequences of nine Cowpox viruses and, by combining them with the available data of 37 additional genomes, confirm polyphyly of Cowpox viruses and find statistical support based on genetic data for more than a dozen species. These results are discussed in light of the current International Committee on Taxonomy of Viruses species definition, as well as immediate and future implications for poxvirus taxonomic classification schemes. Data support the recognition of five monophyletic clades of Cowpox viruses as valid species. View Full-Text

Keywords: Cowpox virus; smallpox; Vaccinia virus; poxvirus; phylogenomics; monophyly; polyphyly; species delimitation; taxonomy; misnomers Cowpox virus; smallpox; Vaccinia virus; poxvirus; phylogenomics; monophyly; polyphyly; species delimitation; taxonomy; misnomers





Autor: Matthew R. Mauldin 1,2,†,* , Markus Antwerpen 3,†, Ginny L. Emerson 1, Yu Li 1, Gudrun Zoeller 3, Darin S. Carroll 1 and Hermann Meyer 3

Fuente: http://mdpi.com/



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