Determination of Glucose Concentration in Aqueous Solution Using ATR-WT-IR TechniqueReportar como inadecuado




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Chemical-Pharmaceutical Engineering Department, School of Applied Medical Sciences, German-Jordanian University, P.O. Box 35247 Amman 11180 Jordan





Abstract Fourier transformation infrared FT-IR spectroscopy has been used to measure glucose concentrations in different matrices. The accuracy of the FT-IR technique does not meet the requirements of medical applications, so we have developed a new, efficient and precise method based on attenuated total reflectance coupled with wavelet transformation ATR-WT-IR. One thousand interferograms, divided into training- and testing-sets, have been recorded from four glucose concentrations using an ATR-IR unit. Signals were subjected to WT and neural network NN study in order to design correlation algorithm. The Pearson’s Correlation Coefficient PCC obtained by judging the predicted- against the real-concentrations was 0.9954, with a mean square error of 8.4e-005. The proposed ATR-WT-IR method shows efficiency in glucose prediction and could possibly to be integrated into a non-invasive monitoring technique. View Full-Text

Keywords: diabetes; biosensors; glucose monitoring; wavelet; neural network; noninvasive sensing; infrared; ATR diabetes; biosensors; glucose monitoring; wavelet; neural network; noninvasive sensing; infrared; ATR





Autor: Samer Ibrahim Al-Gharabli

Fuente: http://mdpi.com/



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