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1

Columbia Institute of Pharmacy, Tekari, Raipur, 493111, Chhattisgarh, India

2

Institute of Pharmacy, Pt. Ravishankar Sukla University, Raipur, 493111, Chhattisgarh, India





*

Author to whom correspondence should be addressed.



Abstract The aqueous extract of Swertia chirata Buch Ham. Root ASC Family: Gentianaceae was evaluated for its antipyretic potential on Brewer’s yeastinduced pyrexia in albino rats and Typhoid-Paratyphoid A, B vaccine induced Hyperexia in rabbits. In both models, the extract, at dose of 200 mg kg−1 body wt. and 400 mg kg−1 body weight, produced significant p<0.001 reduction in elevated body temperature in a dose dependent manner. The antipyretic effect of the extract was comparable to that of paracetamol 150 mg kg−1 body weight, p.o., a standard antipyretic agent.

Keywords: Swertia chirata; Chirayta; Antipyretic; Hyperexia; Fever Swertia chirata; Chirayta; Antipyretic; Hyperexia; Fever





Autor: Sushil BHARGAVA 1,* , Prakash S. RAO 1, Paridhi BHARGAVA 2 and Shivshankar SHUKLA 2

Fuente: http://mdpi.com/



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