Vitamin D Interactions with Soy Isoflavones on Bone after Menopause: A ReviewReportar como inadecuado




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Department of Nutrition Science, Purdue University, 700 W State St, West Lafayette, IN 47907, USA





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Abstract Vitamin D is known to increase Ca absorption in adults. However, the threshold vitamin D status to benefit Ca absorption is lower than the target vitamin D status for higher bone mineral density and lower fracture risk, pointing to another pathway for vitamin D to benefit bone. One possibility is by affecting osteoblast and osteoclasts directly. Vitamin D-related bone metabolism may also be affected by soy isoflavones, which selectively bind to the estrogen receptor β and may reduce bone loss in postmenopausal women. We discuss a possible synergistic effect of soy isoflavones and vitamin D on bone by affecting osteoblast and osteoclast formation and activity in postmenopausal women. View Full-Text

Keywords: vitamin D; phytoestrogen; soy isoflavones; bone; postmenopause vitamin D; phytoestrogen; soy isoflavones; bone; postmenopause





Autor: Clara Y. Park and Connie M. Weaver *

Fuente: http://mdpi.com/



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