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1

Respiratory Epidemiology, Occupational Medicine, and Public Health Group, National Heart & Lung Institute, Imperial College London, London, SW3 6LR, UK

2

Royal Brompton Hospital and Harefield NHS Foundation Trust, Sydney Street, London SW3 6NP, UK

3

Department of Nutrition, Faculty of Medicine, University of Chile, Independencia 1027, Santiago, Chile

4

MRC-HPA Centre for Environment and Health, Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1NY, UK

5

Department of Psychological Medicine, Weston Education Centre, Kings College, London, SE5 9RJ, UK





*

Author to whom correspondence should be addressed.



Abstract Dietary antioxidants may protect against poor ventilatory function. We assessed the relation between ventilatory function and antioxidant components of diet in young Chileans. Forced expiratory volume in 1 s FEV1, forced vital capacity FVC, and the ratio FEV1-FVC were measured in 1232 adults aged 22–28 years, using a Vitalograph device. Dietary intake was ascertained with a food frequency questionnaire FFQ designed for this study, from which nutrient and flavonoid intakes were estimated. Dietary patterns were derived with Principal Component Analysis PCA. After controlling for potential confounders, dietary intake of total catechins was positively associated with FVC Regression coefficient RC of highest vs. lowest quintile of intake 0.07; 95% CI 0.01 to 0.15; p per trend 0.006. Total fruit intake was related to FVC RC of highest vs. lowest quintile 0.08; 95% CI 0.003 to 0.15; p per trend 0.02. Intake of omega 3 fatty acids was associated with a higher FEV1 RC for highest vs. lowest quintile 0.08; 95% CI 0.01 to 0.15 L; p per trend 0.02 and with FVC 0.08 RC in highest vs. lowest quintile of intake 0.08, 95% CI 0.001 to 0.16; p per trend 0.04. Our results show that fresh fruits, flavonoids, and omega 3 fatty acids may contribute to maintain ventilatory function. View Full-Text

Keywords: antioxidants; flavonoids; FFQ; lung function; young adults; general population antioxidants; flavonoids; FFQ; lung function; young adults; general population





Autor: Vanessa Garcia-Larsen 1,2,* , Hugo Amigo 3, Patricia Bustos 3, Ioannis Bakolis 4 and Roberto J. Rona 5

Fuente: http://mdpi.com/



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