The Mediterranean Diet and Cognitive Function among Healthy Older Adults in a 6-Month Randomised Controlled Trial: The MedLey StudyReportar como inadecuado


The Mediterranean Diet and Cognitive Function among Healthy Older Adults in a 6-Month Randomised Controlled Trial: The MedLey Study


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1

School of Psychology, Social Work and Social Policy, University of South Australia, Adelaide 5001, Australia

2

Alliance for Research in Exercise, Nutrition and Activity ARENA, School of Health Sciences, University of South Australia, Adelaide 5001, Australia

3

Flinders Centre for Innovation in Cancer, School of Medicine, The Flinders University of South Australia, G.P.O. Box 2100, Adelaide 5001, Australia

4

School of Medicine and Pharmacology, The University of Western Australia, Perth 6000, Australia





*

Author to whom correspondence should be addressed.



Abstract Evidence from a limited number of randomised controlled intervention trials RCTs have shown that a Mediterranean dietary pattern may reduce the risk of cognitive decline and enhance cognitive function among healthy older adults. However, there are currently no data in non-Mediterranean older adult populations. The present study aimed to address this gap by examining the effect of a Mediterranean dietary pattern MedDiet for six months on aspects of cognitive function in a randomised controlled intervention trial the MedLey study that extended for a duration of 18 months. In the final analysed cohort, a total of 137 men and women mean age of 72.1 ± 5.0 years randomly assigned to either a MedDiet or control diet HabDiet i.e., habitual dietary intake, were assessed on a comprehensive neuropsychological test battery, including 11 individual tests. In multivariable-adjusted models, the MedDiet group did not perform significantly better than the HabDiet control group for executive functioning adjusted mean differences: +2.53, 95% CI −2.59 to 7.65, p = 0.33; speed of processing adjusted mean differences: +3.24, 95% CI −1.21 to 7.70, p = 0.15; memory adjusted mean differences: +2.00, 95% CI −3.88 to 7.88, p = 0.50; visual-spatial ability adjusted mean differences: +0.21, 95% CI −0.38 to 0.81, 0.48; and overall age-related cognitive performance adjusted mean differences: +7.99, 95% CI −4.00 to 19.9, p = 0.19. In conclusion, this study did not find evidence of a beneficial effect of a MedDiet intervention on cognitive function among healthy older adults. View Full-Text

Keywords: Mediterranean diet; cognitive function; randomised controlled trial; older adults Mediterranean diet; cognitive function; randomised controlled trial; older adults





Autor: Alissa Knight 1,* , Janet Bryan 1,2, Carlene Wilson 3, Jonathan M. Hodgson 4, Courtney R. Davis 2 and Karen J. Murphy 2

Fuente: http://mdpi.com/



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