Leufolins A and B, Potent Butyrylcholinesterase-inhibiting Flavonoid Glucosides from Leucas urticifoliaReportar como inadecuado




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1

International Centre for Chemical Sciences, HEJ Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan

2

Medicinal Botanic Centre, PCSIR Labs. Complex Peshawar, Peshawar, N.W.F.P, Pakistan

3

Pharmaceutical Research Centre, PCSIR Labs. Complex, Karachi-75280, Pakistan





*

Author to whom correspondence should be addressed.



Abstract New flavonoidal glucosides leufolins A 1 and B 2, have been isolated from the ethyl acetate soluble fraction of the whole plants of Leucas urticifolia. Their structures were elucidated on the basis of extensive analysis of nuclear magnetic resonance 1D and 2D NMR spectral data. Both of these compounds exhiited significant inhibitory potential against the enzyme butyrylcholinesterase. View Full-Text

Keywords: Leucas urticifolia; Lamiaceae; Leufolin A; Leufolin B; Butyrylcholinesterase; Leucas urticifolia; Lamiaceae; Leufolin A; Leufolin B; Butyrylcholinesterase; Inhibitory activity Leucas urticifolia; Lamiaceae; Leufolin A; Leufolin B; Butyrylcholinesterase; Leucas urticifolia; Lamiaceae; Leufolin A; Leufolin B; Butyrylcholinesterase; Inhibitory activity





Autor: Atia-tun Noor 1, Itrat Fatima 1, Ijaz Ahmad 2, Abdul Malik 1,* , Nighat Afza 3, Lubna Iqbal 3, Mehreen Latif 3 and Sher Bahadar Khan 3

Fuente: http://mdpi.com/



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