Synthesis and Antibacterial Evaluation of Some Novel Imidazole and Benzimidazole SulfonamidesReportar como inadecuado




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Chemistry Department, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia

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Section for Co-curricular Courses, External Faculty Electives and TITAS SKET, University of Malaya, Kuala Lumpur 50603, Malaysia

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Department of Chemistry, Collage of Science for Women, Baghdad University, Aljadriya 10071, Baghdad, Iraq

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School of Biosciences and Biotechnology, Faculty of Science and Technology, University Kebangsaan Malaysia, Bangi 43600, Selangor, Malaysia





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Authors to whom correspondence should be addressed.



Abstract Several new substituted sulfonamide compounds were synthesized and their structures were confirmed by 1H-NMR, 13C-NMR, FT-IR, and mass spectroscopy. The antibacterial activities of the synthesized compounds were screened against standard strains of six Gram positive and four Gram negative bacteria using the microbroth dilution assay. Most of the compounds studied showed promising activities against both types of bacteria. View Full-Text

Keywords: sulfonamide; 4-methylbenzenesulfonamide; 4-nitrobenzenesulfonamide; 4-methoxybenzenesulfonamide; imidazole; benzimidazole; antibacterial activity sulfonamide; 4-methylbenzenesulfonamide; 4-nitrobenzenesulfonamide; 4-methoxybenzenesulfonamide; imidazole; benzimidazole; antibacterial activity





Autor: Nassir N. Al-Mohammed 1,* , Yatimah Alias 1, Zanariah Abdullah 1,2,* , Raied M. Shakir 1, Ekhlass M. Taha 3 and Aidil Abdul Hamid 4

Fuente: http://mdpi.com/



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