Nanocapsular Dispersion of Cinnamaldehyde for Enhanced Inhibitory Activity against Aflatoxin Production by Aspergillus flavusReportar como inadecuado




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1

School of Marine Science, Ningbo University, Ningbo 315211, China

2

Department of Food Science, Henan Institute of Science and Technology, Xinxiang 453003, China



These authors contributed equally to this work.





*

Authors to whom correspondence should be addressed.



Academic Editor: Derek J. McPhee

Abstract Cinnamaldehyde CA is marginally soluble in water, making it challenging to evenly disperse it in foods, and resulting in lowered anti-A. flavus efficacy. In the present study, nano-dispersed CA nano-CA was prepared to increase its aqueous solubility. Free and nano-dispersed CA were compared in terms of their inhibitory activity against fungal growth and aflatoxin production of A. flavus both in Sabouraud Dextrose SD culture and in peanut butter. Our results indicated that free CA inhibited the mycelia growth and aflatoxin production of A. flavus with a minimal inhibitory concentration MIC value of 1.0 mM, but promoted the aflatoxin production at some concentrations lower than the MIC. Nano-CA had a lower MIC value of 0.8 mM against A. flavus, and also showed improved activity against aflatoxin production without the promotion at lower dose. The solidity of peanut butter had an adverse impact on the antifungal activity of free CA, whereas nano-dispersed CA showed more than 2-fold improved activity against the growth of A. flavus. Free CA still promoted AFB1 production at the concentration of 0.25 mM, whereas nano-CA showed more efficient inhibition of AFB1 production in the butter. View Full-Text

Keywords: cinnamaldehyde; nano-dispersion; aflatoxin; inhibition; peanut butter cinnamaldehyde; nano-dispersion; aflatoxin; inhibition; peanut butter





Autor: Hongbo Li 1,2,†, Qingshan Shen 2,†, Wei Zhou 2, Haizhen Mo 2, Daodong Pan 1,* and Liangbin Hu 2,*

Fuente: http://mdpi.com/



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