Negative-Pressure Cavitation Extraction of Secoisolariciresinol Diglycoside from Flaxseed CakesReportar como inadecuado




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1

College of Pharmaceutical Sciences, Soochow University, Suzhou 215123, China

2

Institute of Medicinal Plants, Yunnan Academy of Agricultural Sciences, Kunming 650205, China





*

Authors to whom correspondence should be addressed.



Academic Editor: Nigel Brunton

Abstract The negative-pressure cavitation extraction NPCE technique was applied firstly to extract secoisolariciresinol diglucoside SDG from flaxseed cakes. The significant extraction parameters were screened by fractional factorial design FFD. The optimal parameters were determined using the central composite design CCD with the two variables, NaOH amount and the liquid-solid ratio. The conditions of the extraction were optimized by using response surface methodology RSM. Under the optimal conditions, the extraction yield and the extraction purity of SDG was 16.25 mg-g and 3.86%, respectively. The efficiency of NPCE was compared with that of conventional extraction methods. Our results demonstrated that NPCE was comparable to the well-known ultrasound-assisted extraction in term of extraction yield and purity. This extraction technique has advantages of less time-consuming, low solvent usage and high throughput capability. View Full-Text

Keywords: flaxseed cake; negative-pressure cavitation extraction; pilot-scale application; response surface methodology; secoisolariciresinol diglucoside flaxseed cake; negative-pressure cavitation extraction; pilot-scale application; response surface methodology; secoisolariciresinol diglucoside





Autor: Hao Tian 1,2, Wan-Yi Li 2,* , Dan Xiao 2, Zhi-Min Li 2 and Jian-Wen Wang 1,*

Fuente: http://mdpi.com/



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