Bioactive Cembranoids from the South China Sea Soft Coral Sarcophyton elegansReportar como inadecuado




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1

School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China

2

East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai 200090, China





*

Author to whom correspondence should be addressed.



Academic Editor: John Beutler

Abstract Four new cembranoids, sarcophelegans A–D 1–4 and six known analogues 5–10 were isolated from the South China Sea soft coral Sarcophyton elegans. Their structures were elucidated through detailed spectroscopic analysis, and the absolute configuration of 1 was confirmed by single-crystal X-ray diffraction. The antimigratory potential of compounds 1–10 were evaluated and compounds 2 and 6 were found to inhibit human breast tumor MDA-MB-231 cell migration at 10 μM. View Full-Text

Keywords: Sarcophyton elegans; cembranoids; antimigratory activity Sarcophyton elegans; cembranoids; antimigratory activity





Autor: Xin Liu 1, Junsheng Zhang 1, Qiao Liu 1, Guihua Tang 1, Hongsheng Wang 1, Chengqi Fan 2 and Sheng Yin 1,*

Fuente: http://mdpi.com/



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