Palladium-Catalyzed One-Pot Approach to 3-Diarylmethyleneoxindoles from Propiolamidoaryl TriflateReport as inadecuate




Palladium-Catalyzed One-Pot Approach to 3-Diarylmethyleneoxindoles from Propiolamidoaryl Triflate - Download this document for free, or read online. Document in PDF available to download.

Integrated Research Institute of Pharmaceutical Sciences, College of Pharmacy, The Catholic University of Korea, Bucheon-si, Gyeonggi-do 420-743, Korea



These authors contributed equally to this work.





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Academic Editor: Roman Dembinski

Abstract 3-Diarylmethyleneoxindoles have been synthesized from propiolamidoaryl triflate utilizing a palladium-catalyzed one-pot reaction consisting of three successive reactions: Sonogashira, Heck, and Suzuki-Miyaura. This method allows for the production of a complex skeleton of 3-diarylmethyleneoxindole from propiolamidoaryl triflate using a commercially available aryl iodide and arylboronic acid in a simple and efficient way with moderate yield and stereoselectivity. View Full-Text

Keywords: 3-Diarylmethyleneoxindole; one-pot reaction; aryl triflate; palladium-catalyzed reaction 3-Diarylmethyleneoxindole; one-pot reaction; aryl triflate; palladium-catalyzed reaction





Author: Dahye Lee †, Sunhwa Park †, Yoseb Yu, Kye Jung Shin and Jae Hong Seo *

Source: http://mdpi.com/



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