Identification of N-Acetyldopamine Dimers from the Dung Beetle Catharsius molossus and Their COX-1 and COX-2 Inhibitory ActivitiesReportar como inadecuado




Identification of N-Acetyldopamine Dimers from the Dung Beetle Catharsius molossus and Their COX-1 and COX-2 Inhibitory Activities - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

1

School of Medicine, Sichuan Medical University, 319 Zhongshan Road, Luzhou 646000, China

2

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, 132 Lanhei Road, Kunming 650201, China

3

Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 190 Kaiyuan Road, Guangzhou 510530, China





*

Authors to whom correspondence should be addressed.



Academic Editor: Derek J. McPhee

Abstract Recent studies focusing on identifying the biological agents of Catharsius molossus have led to the identification of three new N-acetyldopamine dimers molossusamide A–C 1-3 and two known compounds 4 and 5. The structures of the new compounds were identified by comprehensive spectroscopic evidences. Compound 4 was found to have inhibitory effects towards COX-1 and COX-2. View Full-Text

Keywords: Catharsius molossus; N-acetyldopamine dimers; COX-1; COX-2 Catharsius molossus; N-acetyldopamine dimers; COX-1; COX-2





Autor: Juan Lu 1,2, Qin Sun 1, Zheng-Chao Tu 3, Qing Lv 2, Pi-Xian Shui 1,* and Yong-Xian Cheng 2,*

Fuente: http://mdpi.com/



DESCARGAR PDF




Documentos relacionados