Phytochemical and Biological Investigation of Two Diplotaxis Species Growing in Tunisia: D. virgata and D. erucoidesReportar como inadecuado




Phytochemical and Biological Investigation of Two Diplotaxis Species Growing in Tunisia: D. virgata and D. erucoides - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

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Faculté des Sciences de Monastir, Université de Monastir, Avenue de lEnvironnement, 5019 Monastir, Tunisia

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Laboratoire de Chimie Organique Structurale, Synthèse et Etude Physicochimique–Faculté des Sciences de Tunis, 2092 El Manar, Tunisia

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Service Central danalyse, Institut des Sciences Analytiques, Université de Lyon, UMR 5280 CNRS, Université

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Laboratoire de Chimie Hétérocyclique, Produits Naturels et Réactivité, Equipe, Chimie Médicinale et Produits Naturels, Faculté des Sciences de Monastir, Université de Monastir, Avenue of the Environment, 5019 Monastir, Tunisia





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Author to whom correspondence should be addressed.



Academic Editor: Maurizio Battino

Abstract A phytochemical investigation of Diplotaxis virgata D.C. and D. erucoides L. D.C. Brassicaceae offered to the isolation of two new flavonoids isorhamnetin-3-O-α-l-glucopyranoside 1 and rhamnetin-3,3ʹ-di-O-β-d-glucopyranoside 2, respectively. Their structures have been elucidated from the extended spectroscopic methods, including 1D- and 2D-NMR, UV and mass spectrometry analysis and by comparison with literature data. The fatty acid composition of the hexane extracts of the two species was also investigated by using GC-MS. The antioxidant activity of ethanol, ethyl acetate, n-butanol extracts and the isolated compounds from the two species was evaluated using DPPH and ABTS+ scavenging assays. All the tested samples showed an efficient radical scavenging ability, with IC50 values ranging from 16–40 µg-mL for the DPPH and from 17–44 µg-mL for the ABTS+ assays. In addition, the antibacterial activity of the prepared extracts and compounds 1 and 2, determined by well diffusion agar method against two Gram positive and five Gram negative bacteria, was evaluated and the results showed significant effects against all strains used. View Full-Text

Keywords: D. erucoides; D. virgata; flavonoids; fatty acids; NMR; antioxidant activity; antimicrobial activity D. erucoides; D. virgata; flavonoids; fatty acids; NMR; antioxidant activity; antimicrobial activity





Autor: Nizar Ben Salah 1,2, Hervé Casabianca 3, Hichem Ben Jannet 4, Sophie Chenavas 3, Corinne Sanglar 3, Aurélie Fildier 3 and Nabiha Bouzouita 2,*

Fuente: http://mdpi.com/



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