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1

College of Forestry, Southwest Forestry University, Kunming 650224, Yunnan, China

2

School of Pharmacy, Wannan Medical College, Wuhu 241002, Anhui, China

3

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, China





*

Authors to whom correspondence should be addressed.



Academic Editor: Derek J. McPhee

Abstract Two new flavonol glycosides, named polygalin H 1 and polygalin I 2, as well as the known compound polygalin D 3, were isolated from the whole plant of Polygala sibirica L. var megalopha Fr. Their structures were elucidated on the basis of spectroscopic data analysis. These flavonol glycosides exhibited strong inhibitory activities against xanthine oxidase in vitro. Their half-maximal inhibitory concentrations IC50 were calculated, which were 9.48, 8.31, 16.00 μM, respectively. View Full-Text

Keywords: Polygala sibirica; Polygalaceae; flavonol glycosides; inhibition of xanthine oxidase Polygala sibirica; Polygalaceae; flavonol glycosides; inhibition of xanthine oxidase





Autor: Yan-Jie Huang 1, Ling-Yun Zhou 1,2, Jun-Min Wang 1, Qiang Li 1, Yuan-Yuan Geng 1, Hai-Yang Liu 3,* and Yan Hua 1,*

Fuente: http://mdpi.com/



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