Two New Clerodane Diterpenes from Tinospora sagittataReportar como inadecuado


Two New Clerodane Diterpenes from Tinospora sagittata


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1

College of Plant Protection, Hunan Agricultural University, Changsha 410128, China

2

Hunan Co-Innovation Center for Utilization of Botanical Functional Ingredients, Changsha 410128, China

3

State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China





*

Author to whom correspondence should be addressed.



Academic Editor: Derek J. McPhee

Abstract Two new clerodane-type diterpenes, tinosporins C 1 and tinosporins D 2 were isolated from the stems of Tinospora sagittata Oliv., together with three known ones, columbin 3, tinophylloloside 4, and tinospinoside D 5. The structures of these compounds were determined on the basis of spectroscopic data interpretation, with that of the absolute configuration of compound 1 was assigned by experimental and calculated ECD spectra. The cytotoxicity and α-glucosidase inhibitory activities of isolated compounds were evaluated in vitro. View Full-Text

Keywords: Tinospora sagittata; clerodane diterpenes; α-glucosidase inhibitory activity Tinospora sagittata; clerodane diterpenes; α-glucosidase inhibitory activity





Autor: Guanhua Li 1,†, Wenbing Ding 1,2,†, Fanghao Wan 1,3 and Youzhi Li 1,2,*

Fuente: http://mdpi.com/



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