Therapeutic Effects of Phytochemicals and Medicinal Herbs on Chemotherapy-Induced Peripheral NeuropathyReportar como inadecuado




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1

Department of Physiology, College of Korean Medicine, Kyung Hee University, 26 Kyunghee-daero, Dongdaemoon-gu, Seoul 02447, Korea

2

Department of Research and Development, National Development Institute of Korean Medicine, 94 Hwarang-ro, Gyeongsan-si, Gyeongsangbuk-do 38540, Korea





*

Author to whom correspondence should be addressed.



Academic Editor: Luigia Trabace

Abstract Chemotherapy-induced peripheral neuropathy CIPN is a frequent adverse effect of neurotoxic anticancer medicines. It leads to autonomic and somatic system dysfunction and decreases the patient’s quality of life. This side effect eventually causes chemotherapy non-compliance. Patients are prompted to seek alternative treatment options since there is no conventional remedy for CIPN. A range of medicinal herbs have multifarious effects, and they have shown some evidence of efficacy in various neurological and immunological diseases. While CIPN has multiple mechanisms of neurotoxicity, these phytomedicines might offer neuronal protection or regeneration with the multiple targets in CIPN. Thus far, researchers have investigated the therapeutic benefits of several herbs, herbal formulas, and phytochemicals in preventing the onset and progress of CIPN in animals and humans. Here, we summarize current knowledge regarding the role of phytochemicals, herb extracts, and herbal formulas in alleviating CIPN. View Full-Text

Keywords: phytochemical; medicinal herb; chemotherapy-induced peripheral neuropathy phytochemical; medicinal herb; chemotherapy-induced peripheral neuropathy





Autor: Gihyun Lee 1,2 and Sun Kwang Kim 1,*

Fuente: http://mdpi.com/



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