Essential Oil Composition and Bioactivities of Waldheimia glabra Asteraceae from Qinghai-Tibet PlateauReportar como inadecuado


Essential Oil Composition and Bioactivities of Waldheimia glabra Asteraceae from Qinghai-Tibet Plateau


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1

College of Science, Tibet University, Lhasa 8500, Tibet, China

2

School of Pharmacy, Fudan University, Shanghai 201203, China

3

School of Life Science, Fudan University, Shanghai 200438, China





*

Authors to whom correspondence should be addressed.



Academic Editors: Olga Tzakou and Derek J. McPhee

Abstract Waldheimia glabra is traditionally used as incense and as an anti-influenza drug by Tibetans in China. Here, we collected W. glabra from the Gangs Rinpoche mountain at an altitude of 5200 m, and analyzed its essential oil by gas chromatography-mass spectrometry GC-MS combined with the retention indices RI. Twenty-seven compounds, representing 72.4% of the total essential oil, were identified, including α-bisabolol 20.2%, valeranone 11.8%, chamazulene 9.9%, spathulenol 8.2%, β-caryophyllene 6.1%, and caryophyllene oxide 5.2%. Bioactivity evaluation of the essential oil revealed that it exhibited potent anti-influenza effect on viruses H3N2 and anti-inflammatory effect by inhibiting the lipopolysaccharide LPS-induced nitric oxide NO production in RAW 264.7 macrophages, but no anti-complementary activity. View Full-Text

Keywords: Waldheimia glabra; Tibetan medicine; essential oil; anti-influenza; anti-inflammatory Waldheimia glabra; Tibetan medicine; essential oil; anti-influenza; anti-inflammatory





Autor: Ji De 1, Yan Lu 2,* , Lijun Ling 2, Nan Peng 3 and Yang Zhong 3,*

Fuente: http://mdpi.com/



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