2-{5-Diphenylmethyl-1,3,4-oxadiazol-2-ylsulfanyl}-N-pyrazin-2-ylacetamideReportar como inadecuado


2-{5-Diphenylmethyl-1,3,4-oxadiazol-2-ylsulfanyl}-N-pyrazin-2-ylacetamide


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1

Department of Studies in Chemistry, Mangalore University, Mangalagangotri-574 199, Karnataka, India

2

Research Department of Chemistry, P. A. College of Engineering, Nadupadavu, Mangalore 574153, Karnataka, India





*

Author to whom correspondence should be addressed.



Abstract S-Alkylation of 5-diphenylmethyl-1,3,4-oxadiazole-23H-thione 3 by 2-chloro-N-pyrazin-2-ylacetamide 2 affords the title compound, 2-{5-diphenylmethyl-1,3,4-oxadiazol-2-ylsulfanyl}-N-pyrazin-2-ylacetamide 4. The intermediate 2, in turn, was prepared by the acetylation of 2-aminopyrazine 1 with chloroacetyl chloride. The structure of the newly synthesized compound is characterized by IR, NMR and mass spectral data. View Full-Text

Keywords: 1,3,4-oxadiazole; pyrazine; S-alkylation; thioether 1,3,4-oxadiazole; pyrazine; S-alkylation; thioether





Autor: Prakash S. Nayak 1, Badiadka Narayana 1,* , Seranthimata Samshuddin 1 and Balladka Kunhanna Sarojini 2

Fuente: http://mdpi.com/



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