5-6-Hydroxy-2,5,7,8-tetramethylchroman-2-yl-2-methyl-pentanoic Acid Methyl EsterReportar como inadecuado


5-6-Hydroxy-2,5,7,8-tetramethylchroman-2-yl-2-methyl-pentanoic Acid Methyl Ester


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1

Graduate Institute of Marine Biotechnology, Department of Life Science and Institute of Biotechnology, National Dong Hwa University, Pingtung 944, Taiwan

2

National Museum of Marine Biology and Aquarium, Pingtung 944, Taiwan

3

Institute of Oceanography, National Taiwan University, Taipei 106, Taiwan

4

Graduate Institute of Natural Products, Chang Gung University, Taoyuan 333, Taiwan

5

Department of Marine Biotechnology and Resources and Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 804, Taiwan

6

Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan

7

Chinese Medicine Research and Development Center, China Medical University Hospital, Taichung 404, Taiwan





*

Author to whom correspondence should be addressed.



Abstract A natural diastereomeric mixture of 5-6-hydroxy-2,5,7,8-tetramethyl-chroman-2-yl-2-methyl-pentanoic acid methyl ester 1, was isolated from the soft coral Sinularia arborea. The structure of 1 was elucidated by spectroscopic methods and 1 displayed a significantly inhibitory effect on the generation of superoxide anion by human neutrophils. View Full-Text

Keywords: Sinularia arborea; tocopherol; superoxide anion Sinularia arborea; tocopherol; superoxide anion





Autor: Kuan-Hua Chen 1,2, Chang-Feng Dai 3, Tsong-Long Hwang 4 and Ping-Jyun Sung 1,2,5,6,7,*

Fuente: http://mdpi.com/



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