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3-Chlorokenpaullone


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Institut für Medizinische und Pharmazeutische Chemie, Technische Universität Braunschweig, Beethovenstr. 55, 38106 Braunschweig, Germany





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Abstract 3-Chlorokenpaullone 9-bromo-3-chloro-7,12-dihydroindolo3,2-d1benz­azepin-65H-one is a novel derivative of the protein kinase inhibitor kenpaullone. The title compound was synthesized by a Fischer indole reaction from 8-chloro-3,4-dihydro-1H-1-benzazepin-2,5-dione and 4-bromophenylhydrazine. It was characterized for structural identity by elemental analysis and spectroscopic methods IR, NMR, EI-MS and checked for purity by HPLC. View Full-Text

Keywords: kenpaullone; paullone; protein kinase inhibitor; Fischer indole synthesis kenpaullone; paullone; protein kinase inhibitor; Fischer indole synthesis





Autor: Oliver C. F. Orban, Ricarda S. Korn, Lisa Unger, Akim Yildiz and Conrad Kunick *

Fuente: http://mdpi.com/



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