An Intriguing Method for Fabricating Arbitrarily Shaped -Matreshka- Hydrogels Using a Self-Healing TemplateReportar como inadecuado


An Intriguing Method for Fabricating Arbitrarily Shaped -Matreshka- Hydrogels Using a Self-Healing Template


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1

Graduate School of Pure and Applied Science, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8577, Japan

2

International Center for Materials Nanoarchitectonics WPI-MANA, National Institute for Materials Science NIMS, 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan

3

Japan Society for the Promotion of Science JSPS, 5-3-1, Kojimachi, Chiyoda-ku, Tokyo 102-0083, Japan

4

Graduate School of Industrial Science and Technology, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo 125-8585, Japan





*

Author to whom correspondence should be addressed.



Academic Editor: Peter Dubruel

Abstract This work describes an intriguing strategy for the creation of arbitrarily shaped hydrogels utilizing a self-healing template SHT. A SHT was loaded with a photo-crosslinkable monomer, PEG diacrylate PEGDA, and then ultraviolet light UV crosslinked after first shaping. The SHT template was removed by simple washing with water, leaving behind the hydrogel in the desired physical shape. A hierarchical 3D structure such as -Matreshka- boxes were successfully prepared by simply repeating the -self-healing- and -photo-irradiation- processes. We have also explored the potential of the SHT system for the manipulation of cells. View Full-Text

Keywords: self-healing material; hydrogel fabrication; biocompatible polymer self-healing material; hydrogel fabrication; biocompatible polymer





Autor: Takeshi Sato 1,2,3, Koichiro Uto 2, Takao Aoyagi 2 and Mitsuhiro Ebara 1,2,4,*

Fuente: http://mdpi.com/



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