A Fatty Acid Glycoside from a Marine-Derived Fungus Isolated from Mangrove Plant Scyphiphora hydrophyllaceaReportar como inadecuado




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1

Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, Hainan, China

2

Haikou Key Laboratory for Research and Development of Tropical Natural Products, Haikou 571101, Hainan, China



These authors contributed equally to this work.





*

Authors to whom correspondence should be addressed.



Abstract To study the antimicrobial components from the endophytic fungus A1 of mangrove plant Scyphiphora hydrophyllacea Gaertn. F., a new fatty acid glucoside was isolated by column chromatography from the broth of A1, and its structure was identified as R-3-hydroxyundecanoic acid methylester-3-O-α-l-rhamnopyranoside 1 by spectroscopic methods including 1D and 2D NMR HMQC, 1H-1H COSY and HMBC and chemical methods. Antimicrobial assay showed compound 1 possessed modest inhibitory effect on Saphylococcus aureus and methicillin-resistant S. aureus MRSA using the filter paper disc agar diffusion method. View Full-Text

Keywords: marine endophyte; secondary metabolite; Scyphiphora hydrophyllacea; R-3-hydroxyundecanoic acid methylester-3-O-α-l-rhamnopyranoside marine endophyte; secondary metabolite; Scyphiphora hydrophyllacea; R-3-hydroxyundecanoic acid methylester-3-O-α-l-rhamnopyranoside





Autor: Yan-Bo Zeng 1,2,†, Hui Wang 1,2,†, Wen-Jian Zuo 1,2, Bo Zheng 1,2, Tao Yang 1, Hao-Fu Dai 1,2,* and Wen-Li Mei 1,2,*

Fuente: http://mdpi.com/



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