New Briarane Diterpenoids from the Gorgonian Coral Junceella junceaReportar como inadecuado




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1

School of Pharmacy, College of Medicine, National Taiwan University, Jen-Ai Rd. Sec. 1, Taipei 101-200, Taiwan

2

Institute of Marine Biotechnology and Resources, National Sun Yat-sen University, 70 Lien-Hai Road, Kaohsiung 80424, Taiwan

3

Graduate Institute of Natural Products, Chang Gung University, Taoyuan 333, Taiwan





*

Author to whom correspondence should be addressed.



Abstract Chemical investigation of Junceella juncea has resulted in the isolation of three new briaranes designated juncenolides M–O 1–3. The structures of these compounds were determined by spectroscopic analysis including 2D-NMR COSY, HMBC and NOESY and HRMS. Compound 1 is a new chlorinated briarane while compound 3 contains a rare methyl ester at C-16. The anti-inflammatory activities tested on superoxide anion generation and elastase release by human neutrophils in response to FMLP-CB were evaluated. View Full-Text

Keywords: Junceella juncea; briaranes; anti-inflammatory activity Junceella juncea; briaranes; anti-inflammatory activity





Autor: Jiun-Yang Chang 1,2, Chia-Ching Liaw 1, Ahmed Eid Fazary 1, Tsong-Long Hwang 3 and Ya-Ching Shen 1,*

Fuente: http://mdpi.com/



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