Lochmolins A–G, New Sesquiterpenoids from the Soft Coral Sinularia lochmodesReportar como inadecuado




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1

Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan

2

Department of Nursing, Meiho University, Pingtung 912, Taiwan

3

Department of Food and Nutrition, Meiho University, Pingtung 912, Taiwan

4

Institute of Oceanography, National Taiwan University, Taipei 112, Taiwan

5

Division of Marine Biotechnology, Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 804, Taiwan





*

Author to whom correspondence should be addressed.



Abstract Seven new sesquiterpenoids, lochmolins A–G 1–7, were isolated from a Taiwanese soft coral Sinularia lochmodes. The structures of these metabolites were elucidated by extensive spectroscopic study. Compounds 1–4 were found to inhibit the accumulation of the LPS-induced pro-inflammatory COX-2 protein in RAW264.7 macrophage cells. View Full-Text

Keywords: soft coral; Sinularia lochmodes; sesquiterpenes; aromadendrane; germacrane soft coral; Sinularia lochmodes; sesquiterpenes; aromadendrane; germacrane





Autor: Yen-Ju Tseng 1, Kuo-Ping Shen 2, Hui-Li Lin 3, Chiung-Yao Huang 1, Chang-Feng Dai 4 and Jyh-Horng Sheu 1,5,*

Fuente: http://mdpi.com/



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