Multifaceted Applications of Chitosan in Cancer Drug Delivery and TherapyReportar como inadecuado


Multifaceted Applications of Chitosan in Cancer Drug Delivery and Therapy


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1

Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA

2

Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA

3

Graduate Program in Biomedical Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA





*

Author to whom correspondence should be addressed.



Academic Editor: Hitoshi Sashiwa

Abstract Chitosan is a versatile polysaccharide of biological origin. Due to the biocompatible and biodegradable nature of chitosan, it is intensively utilized in biomedical applications in scaffold engineering as an absorption enhancer, and for bioactive and controlled drug release. In cancer therapy, chitosan has multifaceted applications, such as assisting in gene delivery and chemotherapeutic delivery, and as an immunoadjuvant for vaccines. The present review highlights the recent applications of chitosan and chitosan derivatives in cancer therapy. View Full-Text

Keywords: chitosan; gene delivery; drug delivery; adjuvant; cancer; nanoparticle chitosan; gene delivery; drug delivery; adjuvant; cancer; nanoparticle





Autor: Anish Babu 1,2 and Rajagopal Ramesh 1,2,3,*

Fuente: http://mdpi.com/



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