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1

Department of Bioethics, Cleveland Clinic, 9500 Euclid Avenue JJ60, Cleveland, OH 44195, USA

2

Department of Obstetrics and Gynecology, Cleveland Clinic Womens Health Institute, 9500 Euclid Avenue A81, Cleveland, OH 44195, USA

3

Genomic Medicine Institute, Cleveland Clinic Center for Personalized Genetic Healthcare, 9500 Euclid Avenue NE50, Cleveland, OH 44195, USA



These authors contributed equally to this work.





*

Author to whom correspondence should be addressed.



Abstract Noninvasive prenatal testing NIPT offers pregnant women a new risk assessment tool for fetal aneuploidy that is superior to conventional screening tests. We conducted focus groups with women who were currently pregnant or had recently delivered in the past year to characterize their perspectives about NIPT and to explore factors they would consider during decision making about its use. Women identified accuracy, early timing, testing ease, and determination of fetal sex as advantages of NIPT over other screens, and the noninvasive method of NIPT as an advantage over diagnostic tests. False positive and false negative results, anxiety, cost and insurance coverage were seen as disadvantages of NIPT. Women who do not want fetal aneuploidy information most likely will not undergo NIPT, despite its advantages over other screening tests. However, given its advantages, the decision to have NIPT is straightforward for women who want genetic information about the fetus. Women emphasized the need to make autonomous, private, and informed choices about NIPT, as they would with any prenatal genetic testing option. These perspectives may guide clinicians to conduct effective and clinically relevant counseling with pregnant women who consider utilizing this new genetic technology. View Full-Text

Keywords: noninvasive prenatal testing; patients’ perspectives; patient decision making noninvasive prenatal testing; patients’ perspectives; patient decision making





Autor: Ruth M. Farrell 1,2,3,* , Mary Beth Mercer 1,†, Patricia K. Agatisa 1,†, Marissa B. Smith 3,† and Elliot Philipson 2,†

Fuente: http://mdpi.com/



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