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Department of Obstetrics and Gynecology, Prenatal and Preimplantation Genetic Diagnosis, Fetal Therapy, Ospedale Microcitemico, via Jenner, 09121 Cagliari, Italy


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Abstract Prenatal screening and testing for trisomy 21 in twin pregnancies poses a number of challenges: the exact estimate of the a priori risk of trisomy 21, the choice of prenatal screening test and-or invasive techniques to employ for the diagnosis and the impact of the result on the options of treatment in case of discordant results within a twin pair or among multiples. These different aspects are discussed below while recognizing that many issues remain unresolved. View Full-Text

Keywords: twins; screening; invasive diagnosis; therapy twins; screening; invasive diagnosis; therapy

Autor: Giovanni Monni * , Ambra Iuculano and Maria Angelica Zoppi



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