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QC Laboratory, Post Harvest Technology Department, Central Institute of Fisheries Education CIFE, Versova, Mumbai 400061 India


Biology Department, Eastern New Mexico University, Portales New Mexico, 88130, USA


Author to whom correspondence should be addressed.

Abstract Bacterial pathogens that are multi-drug resistant compromise the effectiveness of treatment when they are the causative agents of infectious disease. These multi-drug resistance mechanisms allow bacteria to survive in the presence of clinically useful antimicrobial agents, thus reducing the efficacy of chemotherapy towards infectious disease. Importantly, active multi-drug efflux is a major mechanism for bacterial pathogen drug resistance. Therefore, because of their overwhelming presence in bacterial pathogens, these active multi-drug efflux mechanisms remain a major area of intense study, so that ultimately measures may be discovered to inhibit these active multi-drug efflux pumps. View Full-Text

Keywords: efflux pump; antibiotic resistance; MFS; antiporter; Tet; Qac efflux pump; antibiotic resistance; MFS; antiporter; Tet; Qac

Autor: Sanath Kumar 1 and Manuel F. Varela 2,*



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