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1

Department of Anatomy and Developmental Biology, Faculty of Medicine, Nursing and Health Sciences, Monash University, Wellington Road, Clayton, Victoria 3800, Australia

2

Centre for Biospectroscopy and the School of Chemistry, Monash University, Clayton, Victoria 3800, Australia

3

Murdoch Childrens Research Institute, the Royal Childrens Hospital, Parkville, Victoria 3052, Australia

4

Australian Synchrotron, 800 Blackburn Road, Clayton, Victoria 3168, Australia





*

Author to whom correspondence should be addressed.



Abstract Fourier transform infrared FTIR microspectroscopy shows potential as a benign, objective and rapid tool to screen pluripotent and multipotent stem cells for clinical use. It offers a new experimental approach that provides a holistic measurement of macromolecular composition such that a signature representing the internal cellular phenotype is obtained. The use of this technique therefore contributes information that is complementary to that acquired by conventional genetic and immunohistochemical methods. View Full-Text

Keywords: Fourier transform infrared microspectroscopy; pluripotent stem cells; multipotent stem cells; regenerative medicine Fourier transform infrared microspectroscopy; pluripotent stem cells; multipotent stem cells; regenerative medicine





Autor: Julie Cao 1,2, Elizabeth S. Ng 1,3, Donald McNaughton 2, Edouard G. Stanley 1,3, Andrew G. Elefanty 1,3, Mark J. Tobin 4 and Philip Heraud 1,2,*

Fuente: http://mdpi.com/



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