Understanding surface-adsorption of proteins: the Vroman effectReportar como inadecuado



 Understanding surface-adsorption of proteins: the Vroman effect


Understanding surface-adsorption of proteins: the Vroman effect - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Descargar gratis o leer online en formato PDF el libro: Understanding surface-adsorption of proteins: the Vroman effect
It is now well accepted that cellular responses to materials in a biological medium reflect greatly the adsorbed biomolecular layer, rather than the material itself. Here, we study by molecular dynamic simulations the competitive protein adsorption on a surface Vroman effect, i.e. the non-monotonic behavior of the amount of protein adsorbed on a surface in contact with plasma as a function of contact time and plasma concentration. We find a complex behavior, with regimes during which small and large proteins are not necessarily competing between them, but are both competing with others in solution. We show how the effect can be understood, controlled and inverted.



Autor: Pol Vilaseca; Kenneth A. Dawson; Giancarlo Franzese

Fuente: https://archive.org/







Documentos relacionados