Vol 13: Umbelliferone -D-galactopyranoside from Aegle marmelos L. corr. an ethnomedicinal plant with antidiabetic, antihyperlipidemic and antioxidative activity.Reportar como inadecuado



 Vol 13: Umbelliferone -D-galactopyranoside from Aegle marmelos L. corr. an ethnomedicinal plant with antidiabetic, antihyperlipidemic and antioxidative activity.


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This article is from BMC Complementary and Alternative Medicine, volume 13.AbstractBackground: Aegle marmelos L. Corr. Rutaceae, commonly known as bael, is used to treat fevers, abdomen pain, palpitation of the heart, urinary troubles, melancholia, anorexia, dyspepsia, diabetes and diarrhea in Indian traditional systems of medicine. The object of the present study was to evaluate the antidiabetic, antihyperlipidemic and antioxidant oxidative stress of umbelliferone β-D-galactopyranoside UFG from stem bark of Aegle marmelos Correa. in STZ streptozotocin induced diabetic rat. Methods: Diabetes was induced in rat by single intraperitoneal injection of STZ 60 mg-kg. The rat was divided into the following groups; I – normal control, II – diabetic control, III – UFG 10 mg-kg, IV – UFG 20 mg-kg, V – UFG 40 mg-kg, VI – Glibenclamide 10 mg-kg, p.o., once a daily dose. Diabetes was measured by change the level blood glucose, plasma insulin and the oxidative stress were assessed in the liver by estimation of the level of antioxidant markers i.e. superoxide dismutase SOD, glutathione peroxidase GPx, catalase CAT and Malondialdehyde MDA and antihyperlipidemic effect was measured by estimation of total cholesterol, triglycerides, LDL low density lipoprotein cholesterol, HDL high density lipoprotein cholesterol, VLDL very low density lipoprotein cholesterol. However in a study, the increased body weight was observed and utilization of glucose was in the oral glucose tolerance test. Result: Daily oral administration of different dose of UFG for 28 days showed significantly P 



Autor: Kumar, Vikas; Ahmed, Danish; Verma, Amita; Anwar, Firoz; Ali, Mohammed; Mujeeb, Mohd

Fuente: https://archive.org/







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