Vol 3: Sex-Based Differences in Outcomes After Percutaneous Coronary Intervention for Acute Myocardial Infarction: A Report From TRANSLATE-ACS.Reportar como inadecuado



 Vol 3: Sex-Based Differences in Outcomes After Percutaneous Coronary Intervention for Acute Myocardial Infarction: A Report From TRANSLATE-ACS.


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This article is from Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, volume 3.AbstractBackground: Data regarding sex‐based outcomes after percutaneous coronary intervention PCI for myocardial infarction are mixed. We sought to examine whether sex differences in outcomes exist in contemporary practice. Methods and Results: We examined acute myocardial infarction patients undergoing PCI between April 2010 and October 2012 at 210 US hospitals participating in the Treatment with Adenosine Diphosphate Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events after Acute Coronary Syndrome TRANSLATE‐ACS observational study. Outcomes included 1‐year risk of major adverse cardiac events and bleeding according to Global Utilization of Strategies To Open Occluded Arteries GUSTO and Bleeding Academic Research Consortium BARC definitions. Among 6218 patients, 27.5% n=1712 were female. Compared with men, women were older, had more comorbidities, and had lower functional status. Use of multivessel PCI and drug‐eluting stents was similar between sexes, while women received less prasugrel. Unadjusted cumulative incidence of 1‐year major adverse cardiac events was higher for women than for men 15.7% versus 13.6%, P=0.02, but female sex was no longer associated with higher incidence of major adverse cardiac events after multivariable adjustment hazard ratio 0.98, 95% CI 0.83 to 1.15. Female sex was associated with higher risks of post‐PCI GUSTO bleeding 9.1% versus 5.7%, P



Autor: Hess, Connie N.; McCoy, Lisa A.; Duggirala, Hesha J.; Tavris, Dale R.; O'Callaghan, Kathryn; Douglas, Pamela S.; Peterson, Eric D.; Wang, Tracy Y.

Fuente: https://archive.org/







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