Vol 10: Syntheses of fluorooxindole and 2-fluoro-2-arylacetic acid derivatives from diethyl 2-fluoromalonate ester.Reportar como inadecuado



 Vol 10: Syntheses of fluorooxindole and 2-fluoro-2-arylacetic acid derivatives from diethyl 2-fluoromalonate ester.


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This article is from Beilstein Journal of Organic Chemistry, volume 10.AbstractDiethyl 2-fluoromalonate ester is utilised as a building block for the synthesis of 2-fluoro-2-arylacetic acid and fluorooxindole derivatives by a strategy involving nucleophilic aromatic substitution reactions with ortho-fluoronitrobenzene substrates followed by decarboxylation, esterification and reductive cyclisation processes.



Autor: Harsanyi, Antal; Sandford, Graham; Yufit, Dmitri S; Howard, Judith AK

Fuente: https://archive.org/







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